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In randomized controlled trials of semaglutide, participants lost on average 14.9-17.6% of their baseline weight over 68 weeks, according to a study cited in Statnews.com.(6) For the GLP-1 tirzepatide, average losses reached 21.4% at the highest studied dose over 72 weeks.(7) All groups in the controlled trials also received counseling on diet and exercise
Findings in context of the broader literature Our results are consistent overall with a post hoc analysis of pooled SUSTAIN and PIONEER data, which also showed that the effect of semaglutide vs comparators on MACE was largely consistent across different CV subgroups [35]
They do not offer compounded GLP-1 medications
More holistic approach: Combining semaglutide with hormone therapy addresses the root causes of weight gain and provides a sustainable solution
