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Unless a doctor prescribes 1,000 mcg (1 mg) to correct a deficiency, most people should be taking a much lower dose of vitamin B12

Whyte WL et al

Avoid drawing diluent into a syringe that has already touched another vial without sterilization

NNMT Inhibition Mechanism and Optimal Dosing Range 5-Amino-1MQ functions as a small-molecule competitive inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme responsible for methylating nicotinamide