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Tirzepatide also contributed to substantial weight loss in participants with pre-diabetes and obesity or overweight: At week 176, those taking tirzepatide achieved average weight reductions of 15.4% (5 mg), 19.9% (10 mg), and 22.9% (15 mg), respectively, compared to 2.1% for placebo

These findings emphasize the benefits of high-dose semaglutide as part of a comprehensive approach to managing metabolic and cardiovascular conditions, making semaglutide an appealing choice for those needing blood sugar reduction and heart health support

Patients with medullary thyroid carcinoma history, MEN2 syndrome, or severe GI conditions should discuss alternatives with their provider

There are some companies out there that are no longer using BMI restrictions to disqualify patients, like Josie and Willow