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Autophagy is a pathway that mediates the degradation of cytoplasmic proteins and organelles and is regulated by signaling molecules such as unc-51-like kinase 1 (Ulk1), coiled-coil myosin-like BCL2-interacting protein (Beclin1), microtubule-associated protein 1 Light chain 3 (Lc3) and autophagy receptor p62 (P62) [11]

Since tirzepatide slows gastric emptying, there is a theoretical concern about delayed mycophenolate absorption

The treatments must be conducted under medical supervision, with careful screening of patient history, dosage, and duration

Blockade of cysteine (cys) and glutamate (glu) intake involved in the synthesis of GPX4 can trigger ferroptosis by disrupting the GSH/GPX4 axis