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Adequate sleep, calories, and protein Sleep quality after knee surgery, adequate calories, and sufficient protein intake have a direct impact on inflammation control and tissue repair

During protein folding stress, the sirtuin SIRT7 also plays an important role by contributing to repressing nuclear respiratory factor 1 (NRF1) activity, a major transcriptional regulator of mitochondrial genes

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In addition, creating an environment where the cells have adequate anti-inflammatory and antioxidative compounds both pre and post surgery expedite the healing process