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After eight weeks, leg heaviness was reported to be reduced by 60.4% in the Pycnogenol group compared to a reduction of 12.6% in the placebo group

doi: 10.1016/j.ijantimicag.2013.08.022 155

Compared with model control, BPC-157-treated groups showed a significant healing response similar to that of the bFGF-treated group

Shaking looks faster, but it forces the air above the powder into the liquid as foam, and you have to wait for that foam to settle before you can draw so it doesnt save time