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The dose escalation schedule spans 16 to 20 weeks: 0.25 mg for four weeks, 0.5 mg for four weeks, 1.0 mg for four weeks, 1.7 mg for four weeks, and finally 2.4 mg as the maintenance dose
Buteau J, Foisy S, Joly E, et al
A phase 2 open-label study of the safety and efficacy of weekly dosing of ATL1102 in patients with non-ambulatory duchenne muscular dystrophy and pharmacology in mdx mice
3,2931 Within this context, bowel obstruction is uncommon but mechanistically plausible
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