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The studys objectives are to characterize the safety, pharmacokinetics, and tolerability of NPM-139 to support the initiation of a Phase 2 dose-ranging study pending successful results of the Phase 1 study

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In parallel, next-generation sequencing panels targeting MC4R , LEPR , POMC , PCSK1 , and SIM1 should be performed in coordination with a specialized pediatric endocrinology unit

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