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In these STEP trials, most participants experienced mild to moderate symptoms, with the incidence of severe side effects being 9.8% in the semaglutide treatment group and 6.4% in the placebo group

Some documented risks include irritation or inflammation of the colon/rectum, electrolyte imbalance, potential infection, and other serious side effects, particularly if done improperly or too frequently

On average, 54% of MRAs were interpreted as healed SLAP repairs while 46% of MRAs were interpreted as having a re-torn SLAP repair

Visceral fat secretes adipokines, such as leptin and adiponectin, influencing inflammatory responses and insulin sensitivity [82]