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Archived from the original on 15 September 2024
The acquired genetic alterations confer upon the initially transformed atypical melanocytes and later upon the melanoma cells that evolved, a selective advantage over their neighbouring normal cells in terms of fitness and proliferation
GIP also facilitates nuclear translocation of the CREB-regulated transcription coactivator 2 (TORC2), which binds to the LPL promoter to induce its expression
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