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1-2 weeks Appetite and cravings start to decrease 2-6 weeks Noticeable weight loss begins 4-8 weeks Insulin sensitivity improves 3-6 months Testosterone levels begin to drop, and periods become more regular 3-12 months Fertility markers start to improve Even if you decide to take a GLP-1 medication, changing your lifestyle and habits are still essential to see long-term success with balancing your hormones, naturally supporting GLP-1 production, and weight loss

Symptoms of malnutrition include: Brittle hair, hair loss and hair pigment loss Dry, inelastic skin, rashes and lesions Frequent and severe infections Irritability, apathy or inattention Low blood pressure Low body temperature Low heart rate Serious vitamin deficiencies like Wernicke Encephalopathy Weakness, faintness and fatigue Muscle loss Wegovy users may also experience extreme muscle loss

however, residual confounding related to diet, weight loss magnitude, or lifestyle modification cannot be entirely excluded