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One posited mechanism is the activation of phospholipase C (PLC), which, according to some researchers, might subsequently facilitate the release of inositol triphosphate (IP3) and diacylglycerol (DAG)
Additionally, TPZ enhances fluorescent staining of ferrous ions while reducing SLC7A11 and GPX4 expression, thus promoting ferroptosis and hindering the proliferation and migration of osteosarcoma cells ( Pientzehuang (PZH) demonstrates inhibitory effects on the diethylnitrosamine (DEN)-induced hepatocellular carcinoma (HCC) model in rats
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