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How reconstitution creates concentration A vial containing 5 mg of lyophilized semaglutide powder becomes a specific concentration based on how much bacteriostatic water you add: Add 1 mL of water: 5 mg/mL concentration Add 2 mL of water: 2.5 mg/mL concentration Add 5 mL of water: 1 mg/mL concentration More water means lower concentration, which means more units per dose but easier measurement

So while many IBS-D folks might see an improvement in diarrhoea, a subset could experience unpredictable bowel movements, especially during the initial weeks of therapy

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To view a copy of this licence, visit About this article Cite this article Chen, H., Liu, S., Gao, S