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Therefore, a thorough medical history may be helpful for differential diagnosis, but the differentiation of physiological oral mucosal melanin hyperpigmentation from single or multiple melanotic macules based on medical history and on clinical and histological grounds may be impossible as they share the same clinical and microscopical features and both may develop at a young age
Oxidative stress increases blood-brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation
Douros, M.B
Am J Physiol Endocrinol Metab 2024;326:E577-E587
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