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Merck & Co.s cyclic peptide enlicitide decanoate was one of the first two drug candidates the US Food and Drug Administration selected to receive the new Commissioners National Priority Voucher in December
The peptide is often sold through unregulated channels as a 'research chemical' or unauthorised medicine, raising significant concerns about purity, dosage accuracy, and contamination
Patients in STEP 1 were desirous of weight loss as a reason for study participation and received structured lifestyle intervention (which included a 500 kcal per day diet with 150 min per week of physical activity)
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