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Pernicious anemia With pernicious anemiaa frequent cause of B12 deficiencyautoimmune activity destroys the intrinsic factor protein or the cells that make IF, which means the ileum of affected folks cant absorb the vitamin

In conclusion, we show that chronic in vivo GSH deficiency, despite inducing CYP2E1 and hepatic oxidative stress, triggers adaptive mechanisms that protect the liver against ethanol-induced toxicity

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