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Clinical trials suggest tirzepatide produces greater average weight loss (up to 22.5%) compared to semaglutide (up to 14.9%), though individual responses vary and both medications are considered highly effective
Tirzepatide should be used only under the supervision of a licensed healthcare provider, and patients should not obtain prescription medication from unverified sellers or change their dose without medical guidance
6 The results showed: Tirzepatide users lost an average of 22.1% of their starting weight Semaglutide users lost an average of 17.1% of their starting weight While tirzepatide showed greater average weight loss, both medications exceeded the 10% threshold considered clinically significant, with 95.2% of tirzepatide users and 83.1% of semaglutide users achieving this level of weight loss
[1] More broadly, the delayed gastric emptying caused by these medications may affect the absorption timing of some oral medications
