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By influencing hormonal signaling and aggregating in prostate tissue, they assist in regulating cell proliferation, inhibiting inflammation, and promoting apoptosis, so contributing to a potential chemopreventive impact against PCa
Both endothelial cells and pericytes contribute to generate components of the basement membrane, which is a vital component of the BBB, providing structural support, cell anchoring, regulate immune cells, and signaling transduction [1, 29, 30]
Larazotide treatment attenuated the enhanced intestinal permeability and blocked the migration of immune cells from the intestine to the joints (graphical summary in Supplementary Fig