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The expression of some GST isoforms, mainly GST pi1, has also been described in cerebral capillaries isolated from adult humans and developing and adult rats, albeit at lower levels than in the choroid plexus [11, 33]
It is also stable in human gastric juice and has been studied extensively in preclinical models with a strong safety profile across all published literature
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Terpene lactones are relatively well absorbed and can cross the bloodbrain barrier, supporting their proposed neurological effects
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