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By extending their patent protection through these follow-on patents, subject to the outcome of litigation and the terms of any settlements, they potentially stand to extend their market monopoly and increase revenues

A 2025 meta-analysis of 33 placebo-controlled randomized trials involving nearly 6,000 participants found that GLP-1RAs modestly (but significantly) reduced LDL cholesterol and total cholesterol, and interestingly, weight change did not influence these lipid outcomes