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Microbiol Immunol (2013) 57:6373
915,916 Investigations have also demonstrated that muscle atrophy caused by iron overload is connected to the ROS-mediated activation of the ubiquitin-proteasome system
Lipids and cancer: emerging roles in pathogenesis, diagnosis and therapeutic intervention
When cysteine residues in KEAP1 undergo redox oxidation, NRF2 interacts with the Cul3/RING-box protein complex, ultimately leading to NRF2 ubiquitination and subsequent degradation via proteasomes
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