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Pyroptosis Pyroptosis is a form of lytic regulated cell death mediated by the gasdermin protein family [69]
Estrogen plays a major role in cognitive function
The TGF-1/Smad3 pathway is a key driver of this process, inducing the expression of fibrotic markers such as -SMA and collagen I, promoting interstitial remodeling
Lipoic acid has been found to activate the insulin signaling cascade in cultured cells (3, 42, 43), increase GLUT4 translocation to cell membranes, and increase glucose uptake in cultured adipose and muscle cells (44, 45)
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