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While healthy eating, physical activity, and lifestyle changes are essential, they are not always sufficient especially for individuals who have struggled for years with metabolic conditions rooted in inequitable systems

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Despite recent letdowns, such as seeing Pfizer dumping early-stage asset danuglipron or Novo Nordisks semaglutide failing to match placebo in a phase 2, several smaller biotech efforts have seen recent success in NASH

Anyone who becomes pregnant whilst enrolled in a trial should inform their trial team immediately