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CagriSema is meant to be combined with a calorie-reduced diet and increased physical activity
As an example, GSTZ1-1 catalyzes the cis-trans isomerization of 4-maleylacetoacetate to 4-fumarylacetoacetate within the phenylalanine catabolic pathway 21
It simultaneously inhibits lipogenesis, the process of converting excess calories into new fat deposits
These studies often employ daily or twice-daily dosing regimens for periods spanning days to weeks, depending on the condition under investigation, such as tissue repair or gastrointestinal healing
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