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Other risks may include hormone imbalances or water retention

doi: 10.1038/ng1148 69 ChenSZhuHWetzelWJPhilbertMA

Additionally, this would place intracranial pressure control as one of the mechanisms underlying migraine, a pharmacologically-targetable one. Braca added that they plan to conduct a double-blind randomized placebo-controlled study as this was a pilot, exploratory study