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While managing weight with semaglutide, patients often experience muscle wasting

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A Japanese open-label trial, with dapagliflozin, showed positive effects regarding steatosis and fibrosis, measured with non-invasive techniques, through liver stiffness measurement (especially in patients with stiffness equal or greater than 8 kPa), 71 while similar results were reported from the double-blind EFFECT-II study (NCT02279407)

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However, the IM route was the top-ranked statistically, followed by the SL and then the oral routes, but without clinical significance

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This approach maximizes your chance of success while minimizing side effect risk

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