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P-CTX (procollagen type I C-terminal cross-linked telopeptide), a marker of bone resorption, increased significantly in the semaglutide group compared to placebo (p = 0.021)

1 Here, we review the evidence regarding the benefits and adverse effects of GLP-1 receptor agonists, aiming to help guide primary care clinicians in using these agents while taking care of their patients who have type 2 diabetes mellitus or obesity