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Estrogenwhich, much like the collagen in our faces, we lose at a rapid rate come midlifehas many important functions related to weight and body composition: It helps women maintain muscle mass, and it contributes to the regulation of appetite and metabolism
In contrast, in 2018, the long-acting GIPGLP-1 co-agonist tirzepatide was found to have substantial glucose-lowering and weight loss properties, to a greater extent than that achieved by GLP-1R agonism with dulaglutide [68], findings replicated in Phase III trials comparing tirzepatide with semaglutide in people with type 2 diabetes [69]
Montano, M., Oursler, K
Visceral fat is the metabolically active fat stored deep in the abdominal cavity, around the organs not the subcutaneous fat you can pinch, but the kind that functions almost like an endocrine organ itself
