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N-3 and n-6FA compete for the same metabolic enzymes such as cyclooxygenase (COX), cytochrome P450 and lipoxygenase (LOX) leading to metabolites with opposing effects on inflammation, cell proliferation and apoptosis (anti-tumorigenic with n-3FA
doi: 10.4014/jmb.2312.12051 132 LiTYuHSongYZhangRGeM
Nrf2 improves endothelial function by resisting oxidative stress and mitochondrial damage, thereby delaying atherosclerosis (245)
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