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Several in vitro and in vivo studies have demonstrated that DPP-4 inhibitors possess antioxidant, anticancer, and proapoptotic properties, particularly against pancreatic and colon cancer cell lines (HT-29)

Additional consideration should be given to vitamin D (most people are deficient regardless of weight), omega-3 fatty acids for inflammation support, magnesium for muscle function and sleep quality, and electrolytes to replace what is lost through the increased water excretion that accompanies early weight loss

Afamelanotide is authorised as a medicine in certain jurisdictions outside the UK

Image credits: Seventyfour/Adobe Stock (Not the actual photo) For most people, the tan is not expected to be permanent