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Central scotoma and muddled thinking as migraine aura
This "builds over time" narrative is community-reported and aligns loosely with the synaptogenesis framing, but it is anecdote layered on a mechanism story whose foundational papers were retracted
76 Studies have shown that within various cell types, including vascular smooth muscle cells, endothelial cells, adipocytes, hepatocytes, pancreatic islet cells, and renal tubular cells, uric acid can activate NADPH oxidase, a crucial enzyme involved in the generation of reactive oxygen species
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