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APX, which is the first enzyme of the cycle, detoxifies H 2 O 2 by bringing about the peroxidation of AsA and yielding monodehydroascorbate radical (MDHA)

These include: Metformin (used for diabetes or PCOS) Proton Pump Inhibitors (used for acid reflux or GERD) H2 Blockers Birth control pills Certain antibiotics If youre taking these medications long-term, particularly in combination, regular B12 injections might be beneficial

This process creates a competitive interaction between the desired protein and the immobilized stationary molecules, which eventually lets the now highly purified proteins be released