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Although the term ferroptosis is relatively new, the idea of iron-dependent LPO as a mechanism of cell death has been around for more than 60 years [19]

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Rhonda Patrick: And PGC-1 alpha, which is a biomarker for mitochondrial biogenesis, which is the generation of new mitochondria

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investigated infertile PCOS patients with obesity randomly assigned to metformin 1000 mg BID or to metformin 1000 mg BID combined with low-dose liraglutide 1.2 mg/day for 12 week, and demonstrated that weight, BMI, and WC decreased with both treatments, without significant difference between the two arms [59]

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