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Symptoms of anaphylaxis include difficulty breathing, wheezing, coughing, trouble swallowing, tight chest and throat, nasal congestion, sneezing, runny nose, rash, hives, pale, blue, or gray skin color, swollen lips or tongue, vomiting, diarrhea, lightheadedness, fainting, dizziness, lethargy, agitation, confusion, drowsiness, and feeling of doom. In infants, symptoms to look for include: increased sleepiness, sudden drooling, inconsolable crying, fussiness, or irritability

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Accordingly, we also investigated direct prediction of intrinsic solubility using the provided intrinsic-solubility models: we were surprised to find that the performance of these models was markedly worse, with typical values between 0.3 and 0.5

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