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In 2016, the POSEIDON criteria introduced a new stratification system based on oocyte quantity and quality to define poor ovarian reserve, but implementing large randomized controlled trials using this criterion presents significant challenges (Poseidon Group Patient-Oriented Strategies Encompassing IndividualizeD Oocyte Number et al., 2016)

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HDAC inhibition induces EMT and alterations in cellular iron homeostasis to augment ferroptosis sensitivity in SW13 cells

4 In SURMOUNT-1, considerably more tirzepatide than placebo patients experienced GI adverse events, e.g., nausea 30% vs