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This does not mean AOD 9604 has zero effect

Int J Food Sci Nutr (2010) 61(4):36980

What is vitamin B12, and why is it essential

The concentration differences of metabolites in tumor cells and the tumor microenvironment can significantly affect the proliferation, migration, and drug resistance of tumor cells [1], as well as the immune response of immune cells in the microenvironment [11, 12]