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If the activity of any of the GLD-1 pathway genes are eliminated in combination with the activity of any of the GLD-2 pathway genes, a germline tumor results with most germ cells failing to enter meiosis (differentiate) ( gld-1 mRNA and enhance GLD-1 protein translation (Suh et al., 2006, 2009
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Have been diagnosed with multiple endocrine neoplasia or have a family history of the condition
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