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Diabetes is prevalent worldwide and the number of patients is drastically rising, with a predication of 366 million in 2030 due to factors such as obesity, inactivity, aging, and hormonal disorders
A unimolecular approach can provide additional benefits relative to co-administration of individual medicines as there is a single pharmacokinetic profile and metabolic fate and the potential for multiple actions at a single cellular target is more likely
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31 In exploratory analysis, lixisenatide also reduced progression of albuminuria and reduced the incidence of new-onset macroalbuminuria (HR 0.815
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