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Proven 20% MACE reduction in SELECT (obesity) and 26% in SUSTAIN 6 (T2D), while exenatide only achieved non-inferiority in EXSCEL
doi:10.1111/j.1742-6723.2008.01114.x
The UConn researchers reported that when subjects supplemented with 2 grams of l-carnitine per day for three weeks, they had significantly increased resting levels of androgen receptors in their muscle cells
Gastrointestinal side effects are the most commonly reported adverse effects of tirzepatide, with clinical trials showing dose-dependent rates: nausea (20-33%), diarrhea (12-23%), vomiting (9-16%), constipation (11-17%), and abdominal pain
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