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Metformin, a widely used antidiabetics entering cells through the thiamine transporters, is known to reduce intestinal thiamine content in mice (96)
Think of it like watering a plant: an injection is like getting water straight to the roots, guaranteeing it gets where it needs to go
In another, a lifespan trial in Swiss-derived SHR mice (1 g/mouse per month) reported no changes in food intake or body weight, while chromosomal aberrations decreased and maximum lifespan increased [7]
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