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Additionally, mitochondrial permeability transition may cause the outer mitochondrial membrane to swell, burst, and release cytochrome c and mitochondrial matrix components such as apoptogenic factors into the cytosol, which may signal (apoptotic) cell death (Poderoso et al., 2019)
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4.4 Maternal RPM supplementation and offspring performance Considering that embryonic development is the period of extensive epigenetic reprogramming, maternal nutrition during the periconceptional and early pregnancy stages plays a crucial role in establishing the molecular and physiological foundations for fetal growth and long-term offspring performance
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