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Fixed-ratio insulin and GLP-1RA co-formulations have stronger clinical-trial support than many newer nanocarrier, hydrogel, and microneedle systems
It was FDA-approved in 2010 as a weight loss medication for Netherlands HIV patients suffering from lipodystrophy, a condition that leads to an accumulation of fat (adipose tissue) in the abdominal area
Most patients only experience a handful of side effects, if any, and these are usually mild and well-tolerated
These findings also confirm the chronicity of obesity and suggest ongoing treatment is required to maintain improvements in weight and health." A new European consortium known as Sophia (Stratification of Obese Phenotypes to Optimize Future Obesity Therapy), led by scientists at University College Dublin, is now attempting to investigate this in more detail
