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Persistent high blood sugar increases the risk of both acute complications and accelerates long-term microvascular and macrovascular damage

Retatrutide activates three hormone receptors: GIP (glucose-dependent insulinotropic polypeptide), GLP-1 (glucagon-like peptide-1), and glucagon receptors

2025;8:eabk1792

Eur Neuropsychopharmacol 23:12191225 Besteher B, Machnik M, Troll M, Toepffer A, Zerekidze A, Rocktaschel T, Heller C, Kikinis Z, Brodoehl S, Finke K, Reuken PA, Opel N, Stallmach A, Gaser C, Walter M (2022) Larger gray matter volumes in neuropsychiatric long-covid syndrome