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(70) demonstrated that treatment with GIPRA led to dose-dependent reductions in body weight in both wild-type and GLP-1R knockout mice, and this effect was negated by co-administration of a GIPR antagonist
Moreover, it was found that dsPelo- or dsHbs1-treated males showed no significant differences in mortality rates compared to dsGFP-treated control (Supplementary Fig
Among new-onset patients with diabetes receiving standard statin therapy, liraglutide together with metformin improved lipid distribution of LDL and C-reactive protein (CRP) in atherosclerosis [35]
However, in a low Her2-expressing cell line, lower Her2 binding variant (Her2mA-CD3) did not show a significant cell killing at the 0.1 nM when co-cultured with T cells while the parental and Her2mB-CD3 selectively demonstrated significant cell killing at the same concentration
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