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The following represents a theoretical ultra-conservative approach based on monotherapy principles: Hypothetical Ultra-Conservative Schedule: This extended 24-week titration period doubles the typical monotherapy escalation timeline , reflecting the complete absence of interaction data and the overlapping side effect profiles
This conservative approach provides maximum receptor recovery and works well for long-term users planning multiple cycles over a year or more
It is important to approach this question carefully, distinguishing between what clinical trial data has formally reported, what has been observed anecdotally, and what remains biologically plausible but unconfirmed
Karako, E
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