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Notably, therapies could be designed to target these markers, thus providing a means of eliminating the CSC population, attenuating EMT, and curbing metastasis [207]
Under high glucose conditions Ex-4 was able to reverse glucose-induced suppression of proliferation in human Periodontal ligament stem cells (PDLSC) [17] and reduced cellular senescence in hMSC as confirmed by EdU staining, flow cytometry and cell cycle analysis [18]
A personalized approach considering individual bone and cardiovascular risk profiles is essential when prescribing GLP-1RAs to women, particularly those with osteoporosis or high cardiovascular risk
Medication exclusions are becoming more common The number of formulary exclusions has risen steadily over the last decade
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