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Science (New York, N.Y.)
Disadvantages: Because drug release depends on antibody degradation, non-cleavable linkers generally exhibit slower onset of action, which may limit efficacy in situations requiring rapid, high-intensity drug effects
A further study identified that the H19/miR-138/HMGA1 axis was implicated in the regulation of migration and invasion in CRC (106)
A weight loss plateau that does not respond to standard interventions like dietary adjustment or increased exercise may have a thyroid component that only lab work can identify
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