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It is one of the peptides whose mechanism becomes more relevant after 50 because mitochondrial dysfunction is a recognized contributor to post-menopausal fatigue, exercise intolerance, and weight gain
(28) There were no statistically significant differences in amputation risk between GLP-1s, SGLT-2 inhibitors, DPP4-Is, and all other agents
doi: 10.2337/db22-0680 8 HayashiTHiranoTTairaTTokunoAMoriYKobaSet al
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