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3 GSH-responsive and -exhausting metal nanomaterials 3.1 Inorganic nanomaterials Inorganic nanomaterials that have intrinsically unique physicochemical properties and can provide satisfactory functionality show enormous potential in biomedical applications, especially in cancer therapy (Wang et al., 2021a)

The SURMOUNT-1 trial showed average weight loss of 20.9% at the 15 mg dose, with 57% of participants losing more than 20% of body weight

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So while many IBS-D folks might see an improvement in diarrhoea, a subset could experience unpredictable bowel movements, especially during the initial weeks of therapy