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Because studies have evaluated GHK-Cu across multiple cell types (including fibroblasts and keratinocytes) and in preclinical models, it is commonly used to support mechanistic work on aging-related tissue changes, repair biology, and copper homeostasisstrictly within controlled research designs
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Note, too, that elevating or pinching the skin has been found to increase the risk of injury, as the needle may pierce the opposite side of the skin fold and enter the skin of the health care worker (Black, 2013)
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